Although co-exposure to butadiene is a concern in the styrene-butadiene industry, the find-ing of increased cancer risk in the reinforced-plastics industry, where Exposure to noise (<85 dBA p = 0.0001; ≥85 dB(A) p = 0.0192) interacted significantly with styrene exposure. Color blindness in men and women (standardized morbidity ratios 2.3 and 16.6, respectively) was not associated with exposure estimates, but was the type previously reported with styrene. Styrene is moderately toxic but may give severe injuries by inhalation and ingestion.and long term exposure is fatal. Acute (short-term) exposure to styrene in humans results in mucous membrane and eye irritation, and gastrointestinal effects. Health effects of styrene include irritation of the skin, eyes, and the upper respiratory tract. Eye Protection: ... (104F) to form a heat-sensitive explosive peroxide. References. Best practice advice is to control exposure to styrene to a level below the workplace exposure limit (WEL). 1994, Kolstad et al. These documents provide information on the health effects of exposure, the chemical’s toxicity and material for responding to a chemical incident. Acute (short-term) exposure to styrene in humans results in mucous membrane and eye irritation, and gastrointestinal effects. How does styrene gas affect the body? NIOSH considers the recommended environmental limits for styrene to be upper boundaries of exposure. 2010. J Med Toxicol. Acute exposure may also result in gastrointestinal effects. He said chronic (long-term) exposure to styrene … with all sections of the recommended standard should prevent or greatly reduce the risk to exposed workers of adverse effects. 1. Exposure to styrene in air can also irritate the eyes, nose and throat. Styrene 100-42-5 Hazard Summary Styrene is primarily used in the production of polystyrene plastics and resins. Exposure to high concentrations of styrene in air can affect the central nervous system causing tiredness, muscle weakness, problems concentrating and nausea. Atlanta, GA: Centers for Disease Control and Prevention. Agency for Toxic Substances and Disease Registry (ATSDR). Results: The median current styrene exposure was 53.6 mg/g creatinine (interquartile range: 19.5-94.4). This includes monitoring for styrene-related cancers and tumors. Thus, employers should make every effort to maintain exposure concentrations as low as possible. Signs and symptoms of Styrene exposure. According to scientists, inhalation of styrene gas is the major route of exposure in humans. appropriate, to prevent skin contact. 1994). higher levels of styrene exposure or longer times since first exposure (Kogevinas et al. Conclusions: Occupational exposure to styrene is a risk factor for hearing loss, and styrene-exposed workers should be included in hearing loss prevention programs. 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